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Saturated animal fats regulate immune system
Cholesterol can play a decisive role in the regulation of immune system - in particular, it directly and positively affects the activation of T-cells. In this regard, the question arises - prolonged therapy with drugs to lower cholesterol can cause a strong decrease in immune system. This is very important for elderly people who already have immune system rapidly weakening with age. Therefore, people with lower cholesterol are more likely to get cancer and infectious diseases.
www.ncbi.nlm.nih.gov/pmc/articles/PMC3793615/
www.ncbi.nlm.nih.gov/pmc/articles/PMC3660587/
Saturated animal fats prolong life
Studies in mice show that with a low-calorie diet, saturated animal fats (rich in cholesterol) greatly extend life compared to unsaturated fats from vegetable oils or fish.
http://www.ncbi.nlm.nih.gov/pubmed/25313149
In older people, high cholesterol does not increase mortality from cardiovascular diseases, and often even lowers, and at the same time strengthens the immune system, reduces the risk of getting cancer and prolongs life. There are many such studies in humans. Some of them can be read on the links below.
http://www.ncbi.nlm.nih.gov/pubmed/9343498
http://jama.jamanetwork.com/article....ticleid=381733
http://annals.org/article.aspx?articleid=710526
There are even studies on people with accelerated aging. And such studies have shown that saturated animal fat slows down the pace of aging in such people.
http://www.cell.com/abstract/S0092-8674(13)01521-3
http://www.cell.com/cell-metabolism/...showall%3Dtrue
So, in animal and elderly experiments on survival (until all subjects have died), it was shown that saturated animal fats, at least in mice and in elderly people, can prolong life, and in people with accelerated aging they slow down aging.
Cholesterol is safe, and sugar causes atherosclerosis
We have long been afraid that cholesterol is to blame for the fact that it clogs the vessels and causes atherosclerosis. But how then to explain the fact that atherosclerosis develops in people with normal cholesterol in the blood, and often at low content. Of course, high cholesterol, especially "harmful" LDL in the bloodstream, is one of the
risk factors, but not necessarily the cause of atherosclerosis. After all, many people live perfect and long lives with elevated cholesterol. And why only half of people who received a heart attack as a result of atherosclerosis, had increased cholesterol, and the other half atherosclerosis and heart attack developed with normal and even low cholesterol?
risk factors, but not necessarily the cause of atherosclerosis. After all, many people live perfect and long lives with elevated cholesterol. And why only half of people who received a heart attack as a result of atherosclerosis, had increased cholesterol, and the other half atherosclerosis and heart attack developed with normal and even low cholesterol?
Vascular atherosclerosis can also develop in those who have low cholesterol levels in the blood. On the contrary, half of people with high cholesterol in the bloodstream do not develop atherosclerosis. And this is because cholesterol itself does not clog the vessels. To force cholesterol to clog the vessels, there must be damage to the endothelial vessels. Consider the factors of endothelial damage:
- High blood pressure.
- Diabetes.
- High blood insulin levels due to food with a high glycemic index.
- Damage to blood vessels under the influence of smoking.
- High levels of homocysteine in the blood.
- Damage to blood vessels by hepatitis viruses.
- Drugs and smoking.
- Senescent (aging) cells.
The chain of events is this: we eat a lot of sugar and foods with a high glycemic index, which are essentially the same sugar. Sugar quickly enters the bloodstream and raises strongly the level of insulin in the blood. And because of insulin on the same day, blood pressure can rise, as insulin activates the sympathetic nervous system. And sugar causes glycation of proteins, because of which the walls of vessels become unelastic, and also gradually raises blood pressure. In addition, sugar activates angiotensin, which is responsible for blood pressure.
http://secure.jbs.elsevierhealth.com...n/cookieAbsent
http://health.passion.ru/novosti-zdo...avlenie-94598/
http://www.ncbi.nlm.nih.gov/pubmed/25475355
Thanks to sugar, a person quickly gains excess body weight, and type 2 diabetes develops. And it turns out that if a person does not have bad habits, has not had hepatitis, has a low level of homocysteine, then he still gets atherosclerosis with age and, as a result, stroke and heart attack. And it's all about sugar. Also, thanks to sugar, the process of glycation of the apoprotein (ApoB100) occurs as part of the “bad cholesterol” of LDL, which leads to the loss of its ability to interact with tissue receptors, it begins to be perceived by the cells of the immune system as a stranger.
As a result, antibodies to this protein are synthesized, and LDL interact with immune cell receptors - macrophages and are phagocytosed. Macrophages that receive a lot of cholesterol die, and cholesterol crystals are deposited in the vessels. Therefore, patients with diabetes mellitus are characterized by early atherosclerosis - after all, with diabetes, glycation with sugar is much faster.
http://5fan.ru/wievjob.php?id=26175
www.ncbi.nlm.nih.gov/pubmed/26493158
www.ncbi.nlm.nih.gov/pubmed/18000963
www.ncbi.nlm.nih.gov/pubmed/10681406
Then why have cholesterol been blamed for heart disease for many years, and why is atherosclerosis often found in people with normal and even low cholesterol?
And the thing is that high cholesterol simply accelerates an existing problem - damage to the endothelium of blood vessels and inflammation in them. And high blood cholesterol in studies is corny statistically easier to associate with atherosclerosis, which was done at the very beginning of observational scientific studies of cholesterol. Because of this, cholesterol was prematurely declared the source of all ills. And that's why a simple decrease in cholesterol does not solve the problem of the progress of atherosclerosis, but only slows down the process.
http://biomolecula.ru/content/1199
http://www.ravnskov.nu/cholesterol.htm
http://www.thincs.org/index.htm
http://qjmed.oxfordjournals.org/cont...2/927.full.pdf
http://ajcn.nutrition.org/content/ea...27725.abstract
http://www.ncbi.nlm.nih.gov/pubmed/19364995
So - the main enemy of our heart is not cholesterol, but sugar. Less commonly, atherosclerosis also develops for other reasons: homocysteine, hepatitis virus, smoking, drugs, senescent (aging cells).
Glucose from sugar accelerates human aging:
www.ncbi.nlm.nih.gov/pubmed/18400054
Medicine about the benefits of cholesterol and the dangers of sugarWhat does modern Western medicine and dietetics say about cholesterol and sugar, and about their role in atherosclerosis and cardiovascular diseases.March 4, 2015 in the new World Health Organization guidelines for adults and children of all countries, it is STRONGLY recommended to reduce your daily intake of free sugars to less than 5% of your total energy consumption. The WHO indicates that hidden sugar is found in foods: honey, syrups, fruit juices, ketchup, sodas. According to the WHO, sugar causes obesity, type 2 diabetes and tooth decay. Diabetes mellitus is proven to cause vascular atherosclerosis and heart disease. Today, in fact, we eat sugar 10 times more than its safe level according to the WHO.
http://www.who.int/mediacentre/news/...-guideline/en/
And here there are conclusions of the February 26, 2015 “Nutrition Guide for Americans,” published by the Ministry of Health and Social Services and the Ministry of Agriculture once every 5 years, starting in 1980. It covers all scientific research in the field of health. One of the recommendations is: “Cholesterol is not dangerous, contrary to what was previously thought. Cholesterol from food does not increase blood cholesterol.
http://www.medicinenet.com/script/ma...iclekey=187168
So, according to the WHO, sugar is dangerous and causes diabetes and atherosclerosis, and cholesterol from saturated animal fats is not dangerous, since it does not cause an increase in blood cholesterol.
Saturated animal fats are better than vegetable fats
Which fat is harmful and which is good? Here are links from which you can understand that saturated fats should not be replaced with vegetable polyunsaturated fats.
www.ncbi.nlm.nih.gov/pubmed/21118617
www.bmj.com/content/346/bmj.e8707
Another thing is that some vegetable fats are also useful. So, for example, vegetable oils with a high content of oleic fatty acid are useful: olive oil and some other oils. Yes, and studies on mice showed that saturated fats are more beneficial and that a combination of saturated and monounsaturated prolongs life more than fish oil, as well as other polyunsaturated ones.
http://www.ncbi.nlm.nih.gov/pubmed/25313149
Therefore, most likely, the best combination would be olive oil with some animal fats - for example, lard or kefir.
Saturated animal fats can slow down aging, make it easier to reduce body weight, lower the risk of heart disease, lower cholesterol, lower the risk of type 2 diabetes, lower the risk of malignant tumors, strengthen immune system, prolong life of people.